What is the mathematical expression of the genetic equilibrium forgenes with two alleles? Is this statistical distribution the sameas the statistical distribution of the respective phenotypes?
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| Mr. and Mrs. Brown want to have children, but Mr. Brown is hesitant. He had an older brother who died of a genetic disorder, and he is worried that he may have a gene that can be passed on. "It's recessive," he tells you, "and doesn't always show up; it can skip a generation."
What are the statistical chances of their children having the genetic disorder? What are the statistical chances of their children 'carrying' the genetic disorder? (define the term 'carrier') How are future generations of their off-spring vulnerable to this condition? How does the occurrence of such a genetic disorder potentially change over several generations? Explain Mr. Brown's concept of 'skipping generations'. |
