Question

QUESTION 1

In the bacterial lac repressor, which of these occurs: (select all that apply)

		(a)In the presence of glucose and the absence of lactose, the repressor is actively produced.
		(b)The lac operon can be hyper-induced in the presence of low glucose by the 'cAMP binding protein' (CAMP).
		(c)In the presence of lactose and the absence of glucose the lac operon is repressed.
		(d)Allolactose is a byproduct of β-galactosidase, indicating high lactose when it builds up.

1.5 points

QUESTION 2

In eukaryotes the enhancer elements can be quite a distance upstream or downstream from the promoter, and transcriptional regulation is helped by protein:protein interactions.

True

False

1.5 points

QUESTION 3

The prokaryotic promoter contains a TATA box that is at -10bp upstream from the transcriptional start site.

True

False

1.5 points

QUESTION 4

During the addition of the poly A tail which of these occurs:(select all that apply)

		(a)The transcript is synthesized beyond the poly A site (AAUAAA).
		(b)The mRNA contains a 5’ cap.
		(c)The transcript is cleaved 35nt downstream from the poly A site.
		(d)An enzyme complex containing an exonuclease and polyadenylate polymerase cleaves nearby the AAUAA site.
		(e)100-300 A’s are added to the 5’ end.