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What feature of DNA methylation allows it to be maintained through DNA replication?

The CpG configuration
Restriction endonuclease sites
Histone modification
The Xist gene

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Sixta Kovacek
Sixta KovacekLv2
28 Sep 2019

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Related questions

1. how does royal jelly explain the epigenetic queen phenotype?

2. Methylation of DNA is the best understood mechanism of epigenetics; however epigenetic changes can also occur through modification of histone proteins. What are four things that can be added, post translationally, to histone proteins?

*Histone acetylation generally destabilizes structure; cause it to assume a more open configuration. Histone acetylation is associated with increased transcription.

*Histone methylation influence on transcription depends on context.

*Epigenetic effect of RNA molecules: Xist example

How does DNA methylation affect gene expression? (Be sure to explain the mechanisms involved.) What characteristic of DNA allows methylation patterns to be maintained through replication and cell division?

Epigenetic modifications to DNA sequences and resulting alterations in chromatin structure can be analyzed by examining DNA methylation and histone modifications. To examine methylation of a DNA sequence, you treat it with sodium bisulfite. a.) If your original DNA sequence is: ACAGTCCGTCGGAGCCTGCCAGTCGCACCT and your sequence after treatment reads: ACAGTTCGTCGGAGCTTGTTAGTCGCACTT, which positions on the original DNA sequence are methylated? (Indicate methylations with an * after the affected nucleotide) b.) When this DNA sequence is replicated, which of these methylations will be transferred to a new sequence? Indicate what the new sequence will be in the standard 5' to 3' direction. c.) How does an increase in DNA methylation affect chromatin structure and what does this do to gene expression? Be specific. d.) Describe how chromatin structure is altered in the process of X-inactivation and how the active X-chromosome prevents itself from being inactivated. Include the functions of Jpx, Xist, Tsix, and describe what each of these gene products do. Be specific.

Genetics Question

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