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peardeer710Lv1
28 Sep 2019
You are studying a C. elegans gene muv-5 that is needed for vulval cell lineages. You have a collection of recessive mutations in muvâ5 that cause the multivulva phenotype. You want to clone the gene to characterize its function. Another student in the lab has been screening for multivulva mutants in a strain with high frequency of transposition. This student finds a muv-5 mutant in her collection and offers it to you.
a. How can a transposable element insertion help you clone your gene?
b. What differences should you expect to find between your transposable element allele and your chemical mutagen-induced mutations?
You are studying a C. elegans gene muv-5 that is needed for vulval cell lineages. You have a collection of recessive mutations in muvâ5 that cause the multivulva phenotype. You want to clone the gene to characterize its function. Another student in the lab has been screening for multivulva mutants in a strain with high frequency of transposition. This student finds a muv-5 mutant in her collection and offers it to you.
a. How can a transposable element insertion help you clone your gene?
b. What differences should you expect to find between your transposable element allele and your chemical mutagen-induced mutations?
Patrina SchowalterLv2
28 Sep 2019