Log in
Biology
2
answers
0
watching
97
views

Indicate all of the following statements that are true.

Options: 1. ATP is an indirect product of the citric acid cycle

2. Acetyl CoA can increase the pool of citric acid cycle intermediates

3. Fatty acids can increase the pool of citric acid cycle intermediates

4. ADP inhibits α-ketoglutarate dehydrogenase

5. The pool of mitochondrial oxaloacetate can be increased by pyruvate

6. All enzymes of the citric acid cycle are found soluble and free in the mitochondrial matrix

Watch
2
answers
0
watching
97
views

For unlimited access to Homework Help, a Homework+ subscription is required.

Unlock all answers

Get 1 free homework help answer.
Already have an account? Log in
Share
Trinidad Tremblay
Trinidad TremblayLv2
28 Sep 2019
Already have an account? Log in
Share

Related textbook solutions

Molecular Cell Biology
8 Edition,
Lodish
ISBN: 9781464183393
Biology: Science for Life with Physiology
6 Edition,
Belk
ISBN: 9780134555430
Biology
2nd Edition, 2013
Openstax
ISBN: 9781947172517
Concepts of Biology
OER Edition,
Openstax
ISBN: 9781938168116
Essentials of Biology
5 Edition,
Mader
ISBN: 9781259660269

Related questions

1. Choose the TWO correct statements describing the citrate cycle.

ATP is an indirect product of the citric acid cycle

Acetyl CoA can increase the pool of citric acid cycle intermediates

Fatty acids can increase the pool of citric acid cycle intermediates

ADP inhibits α-ketoglutarate dehydrogenase

The pool of mitochondrial oxaloacetate can be increased by pyruvate

All enzymes of the citric acid cycle are found soluble and free in the mitochondrial matrix

2.Which molecule in the net reaction of the citrate cycle contributes to the inhibition of pyruvate dehydrogenase?

NADH

H+

H2O

FAD

3. How would a high NADH to NAD+ ratio be expected to affect the pyruvate dehydrogenase reaction?

The E1 subunit is phosphorylated by pyruvate dehydrogenase kinase, and the catalytic activity of pyruvate dehydrogenase decreases.

The last step of the pyruvate dehydrogenase reaction is blocked, resulting in a decrease in activity.

The pyruvate dehydrogenase phosphatase-1 enzyme would increase, resulting in pyruvate dehydrogenase activation at an accelerated rate.

The pyruvate dehydrogenase kinase enzyme activity would increase, resulting in an increase in pyruvate dehydrogenase activity.

Select all of the following statements that are true concerning the citric acid cycle:

______________________

__ NAD+ an FAD become reduced.
__ High-energy carbon dioxide molecules will be generated by substrate-level phosphorylation.
__ ATP is synthesized by chemiosmosis.
__ The organic carbon (from acetyl CoA) that enters the cycle will be completely oxidized in the mitochondrial matrix.
__ Citrate must be continuously regenerated to prepare the cycle to process incoming acetyl CoA.
__ Upon entry into the citric acid cycle, acetyl CoA is combined with oxaloacetate.
__ Two ATP molecules will be consumed for each acetyl CoA that is processed by the cycle.
__ Organic molecules are oxidized in several different steps of the cycle.

1. Integrated metabolism

A. A molecule of glucose that you eat can eventually be transformed into part of a fatty acid that you store. Circle the pathways/cycles below that are part of this overall flow of carbon atoms. Cross out any that are not.

Gluconeogenesis, beta-oxidation, citric acid cycle, glycolysis, urea cycle, fatty acid synthesis

B. Trace the metabolic path of this glucose molecule through the enzymes it encounters along the way to being made into fat. Write all the enzymes in the list below into the proper places in the figure below. If the enzyme is not used, write its name in a “not used" column. If it is used, write the enzyme in the order that the carbon atoms from glucose encounter the enzymes.

Pyruvate dehydrogenase, fumarase, aldolase, lactate dehydrogenase, pyruvate kinase, acetyl CoA carboxylase, fatty acid synthase, hexokinase, carnitine acyltransferase, ATP synthase

B. What is the minimum number of glucose molecules that would be necessary to be the carbon source for synthesis of a 16-carbon fatty acid through this pathway?

C. How many net glucose can be made from one molecule of a 16-carbon fatty acid?

2. Describe each cycle/transport system (compounds, compartments, tissues) and explain its purpose:

A. citrate transport system

B. Cori cycle

C. glucose/alanine cycle

3.

Explain the logic of these pathway regulations:

A. Phosphofructokinase, not hexokinase, is the main regulation site of glycolysis.

B. SuccinylCoA inhibits the entry of acetyl CoA into the citric acid cycle.

C. NADH inhibits pyruvate dehydrogenase.

D. Citrate inhibits the citric acid cycle and activates acetyl-CoA carboxylase.

E. Insulin leads to activation of glycogen synthase.

Weekly leaderboard

Home
Homework Help 3,900,000
Biology 460,000
Start filling in the gaps now
Log in