What are the similarities between the three types of cytoskeleton fibers? (microtubules, microfilaments, intermediate filaments)

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Elin HesselLv2

28 Sep 2019

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2. Cytoskeleton components (microfilaments, microtubules and intermediate filaments) are often compared to railroad tracks, which are built by laying down one railroad at a time. Explain why this analogy can describe how the cytoskeleton is built. How does this analogy fall short of illustrating the dynamic instability of cytoskeleton components?

Explain how the arrangement of the cytoskeleton determines the cell's shape and polarity and provides organization and motility to its organelles.

Explain how microfilaments cooperate with microtubules and intermediate fibers in the normal functioning of cells. Explain how the cytoskeleton participates in the functional organization of tissues.Examine various types of adhesive molecules found on the surfaces of cells and in the surrounding extracellular matrix.

1. How does the extracellular matrix affect a cell that it surrounds? (Select all that apply.)

	The cell's shape depends in part on the structure and composition of the extracellular matrix.
	The genes that the cell expresses depend in part on the types of proteins in the extracellular matrix.
	The size that the cell grows to depends in part on the polysaccharides in the extracellular matrix.
	The extracellular matrix has no effect on the cells that it surrounds.
	All of these choices are correct.

2. Which of the following enable(s) the movement of cells?

	microtubules
	microfilaments
	intermediate filaments
	microtubules and microfilaments
	microfilaments and intermediate filaments

3. Microtubules increase in length:

	more quickly at one end than the other.
	by growing outward from the centrosome.
	in cycles, following rapid depolymerization.
	if free tubulin dimers are available.
	All of these choices are correct.

4. Dynamic instability is the rapid assembly and disassembly of:

	microfilaments.
	intermediate filaments.
	microtubules.
	both microfilaments and microtubules.

5. Which one of the following is a characteristic shared by integrins and cadherins?

	Both are peripheral membrane proteins.
	Both facilitate the adhesion of cells to extracellular matrix proteins.
	Both are present in adherens junctions, desmosomes, and hemidesmosomes.
	The cytoplasmic domains of both proteins are connected to the cytoskeleton.