3
answers
0
watching
354
views
28 Sep 2019
1. 2,3-biphosphoglycerate (BPG) regulates high altitude adaptation. The BPG concentration increases from 5 mM at sea level to 8 mM at an altitude of 4500 m in human blood. Please explain how our blood manages to transport enough oxygen at high altitude. If the BPG concentration does not change, how much less oxygen can the blood transport at 4500 m compared to at sea level? (Answer these questions according to the binding curve of hemoglobin for O2 at different BPG concentration). A mutation of hemoglobin reduces the binding affinity of BPG, how will this mutation affect oxygen binding and the oxygen binding curve?
1. 2,3-biphosphoglycerate (BPG) regulates high altitude adaptation. The BPG concentration increases from 5 mM at sea level to 8 mM at an altitude of 4500 m in human blood. Please explain how our blood manages to transport enough oxygen at high altitude. If the BPG concentration does not change, how much less oxygen can the blood transport at 4500 m compared to at sea level? (Answer these questions according to the binding curve of hemoglobin for O2 at different BPG concentration). A mutation of hemoglobin reduces the binding affinity of BPG, how will this mutation affect oxygen binding and the oxygen binding curve?
Nelly StrackeLv2
28 Sep 2019
Already have an account? Log in