DNA Methylation
A. Name two mechanisms by which it inhibits gene expression
B. How can it activate gene expression?
C. How is methylation passed from one cell to its daughter?
D. How does methylation from the mother and father affect expression of the IGF2 gene?
E. When does imprinting get erased during the life cycle and when does it get established again? Is it completely erased?
DNA Methylation
A. Name two mechanisms by which it inhibits gene expression
B. How can it activate gene expression?
C. How is methylation passed from one cell to its daughter?
D. How does methylation from the mother and father affect expression of the IGF2 gene?
E. When does imprinting get erased during the life cycle and when does it get established again? Is it completely erased?
Related textbook solutions
Related questions
6) ene expression controlled by the epigenome is flexiblebecause the epigenome can respond to environmental signals
Select one:
a) in a time-dependent manner.
b) because the chemical bonds in methyl groups can readilybend.
c) by changing the DNA sequences of genes.
d) similarly to the way that the food supply controlsappetite.
e) in a way that is completely unpredictable.
7) Which of the following can be determined from the DNAfingerprint of an individual?
A DNA fingerprint can reveal
Select one or more:
a) the indvidual's gender (male or female).
the individual's gender (male or female).
b) the individual's blood type.
c) the individual's biological family relationships (paternity,etc.).
d) how many siblings (brothers and sisters) are found in thefamily of the individual whose DNA is sampled.
e) the individualâs risk of heart disease.
8) CODIS is the FBI abbreviation for a database containingthe
Select one or more:
a) digital images of convicted felons.
b) skin fingerprints of convicted felons.
c) genome sequence from the Human Genome Project.
d) DNA libraries available from published research findings.
e) DNA fingerprints of convicted offenders, arrestees, and crimescene samples.
9) Do identical twins have identical skin fingerprints?
Select one:
a) No, because the twins' skin fingerprints are left-rightmirror images of each other due to the mirror image symmetry thathappens when identical embryos split apart from one originalembryo.
b) It depends. If the identical twins are in the same placenta,they will have the same fingerprints. If they are in separateplacentas, they will have different fingerprints.
c) Yes, because identical twins have the same genome and genesthey will have identical skin fingerprints.
d) No, because the development of the skin fingerprints areinfluenced by the environment in the uterus.
e) Yes, because the twins' skin fingerprints are inheriteddirectly from the mother without a contribution from thefather.
10 )
| In the process of Somatic CellNuclear Transfer in which Dolly the sheep was cloned, an adultnucleus was inserted into a denucleated egg cell. How is theepigenome related to this process? |
Select one:
a) The methylation of the adult nucleus must be removed so thatthe cloned zygote can become a viable embryo and fetus.
b) Dolly's epigenome was a mixture of the epigenomes of thedonor mother and of the egg cell from the surrogate mother.
c) The epigenome of the adult nucleus directs development of thecloned zygote.
d) The epigenome of the female surrogate that carried thepregnancy to term becomes impinted on the genome of the clonedzygote.
e) The epigenome of the egg cell nucleus is transferred to thedonor cell nucleus.
