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How does aspirin work? Name enzymes if possible, and describe what this has to do with arachadonic acid which is a ___(A)____ ___(B)___ containing __(C)_ carbons and 4 ___(D)____. (fill in blanks)

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Nelly Stracke
Nelly StrackeLv2
28 Sep 2019

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Related questions

3. Carbohydrates A. Carbohydrate digestion begins in the oral cavity. Name the enzyme that initiates carbohydrate digestion. Name the 3 sets of organs that secrete this enzyme. B. Describe how carbohydrates are chemically digested in the small intestine. Include a discussion of brush border enzymes. C. Does the pancreas release any enzymes which chemically digest carbohydrates? If yes, name it (them). How does pancreatic juice enter the small intestine? D. Fiber (AKA cellulose in plant cell walls) is not digestible. Why not? Despite not being digestible, fiber is beneficial to our health. Why?

4. Proteins A. Where are proteins first digested chemically? What enzyme initiates protein digestion? B. Does the pancreas release any enzymes that chemically digest proteins? If yes, name it (them). C. Describe 3 ways in which the body uses these protein subunits.

___ 25- The Krebs cycle begins with the union of acetyl CoA with oxaloacetate forming citrate, allowing oxidative decarboxylation reactions to occur, and ends with the conversion of malate to oxaloacetate. Using this information and your knowledge of the Krebs cycle, how many net carbons does the citric acid cycle gain?
A) 0 carbons
B) 1 carbon
C) 2 carbons
D) 4 carbons
___ 26- Directly from the Krebs cycle we can obtain:
A) ATP
B) GTP and NADPH
C) ATP and NADPH
D) ATP, GTP, and NADPH
___ 27- Which of the following is not an intermediary of the Krebs cycle?
A) oxaloacetate
B) citrate
C) succinyl CoA
D) acetyl CoA
___ 28- How many di nucleotides are reduced by four turns of the Krebs cycle?
A) 1 FADH2 and 4 NADH
B) 2 FADH2 and 8 NADH
C) 4 FADH2 and 12 NADH
D) 1 FAD and 4 NAD +

The next day a representative from Bristol Myers Squibb (note that two large drug companies market this drug) visits your office and tells you that Plavix® (the generic name is clopidogrel) decreases cardiovascular events by 8.7% compared to aspirin. That sure sounds good to you, as you have lots of elderly patients at risk and many are already on aspirin. The brochure quotes the CAPRIE study, and you decide to investigate further. A Google search reveals that in this 1996 study patients on Plavix® experienced cardiovascular events 9.78% of the time compared to 10.64% of the time with aspirin. Plavix® was approved by the FDAbased on this one study.

What % is the Experimental Event Rate (EER)?

What % is the Control Event Rate (CER)?

What is the Absolute Risk Reduction (ARR)?

Calculate the NNT - use 100 as the numerator.

How much does Plavix® cost monthly?

How much does the generic, Clopidogrel, cost monthly?

How much does the low dose (81 mg) aspirin cost monthly?

The dosage for all of these drugs is 1 tablet taken once a day.

Do the COPE calculations for Plavix, the generic, and aspirin (3 separate calculations) - you may use 1 year as the time interval.

What does the COPE calculation tell you?

Which drug would you be more likely to prescribe and why.

Be sure to include your actual calculations/math

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