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Explain how low doses of arsenic is used to treat leukemia.
Explain how cancer is formed as a result of chemical exposure.
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Keith Leannon
Keith LeannonLv2
28 Sep 2019

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Related questions

Arsenic has a long history of use as a homicidal agent (“arsenic poisoning”). However, in the past 100 years arsenic, it has been used as a pesticide, a treatment for cancer, and a component of consumer products. In some areas of the world, high levels of arsenic are naturally present in drinking water and represent a safety concern. Arsenic occurs in several different forms, including trivalent (arsenites) and pentavalent (arsenate), and the toxic effects can vary significantly depending on the form that is ingested.

During class, we discussed the glycolysis pathway and the reactions that occur during this important process. Explain how the pentavalent form of arsenic (i.e., arsenate) can affect the glycolysis pathway.

In your answer, describe:

(1) Which specific step in the glycolysis pathway is affected by arsenate (include whether arsenate acts as a competitive or noncompetitive inhibitor of this step)? AND

(2) How do the effects of arsenate on this step alter the overall process of energy production (include whether it affects the production of ATP, NADH, or pyruvate)?

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1. What is autoimmunity? What genetic evidence points to autoimmunity being a result of failure of tolerance? (3 marks)

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