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1. Keeping GPCR --- G-proteins ---- Adenylyl Cyclase ----Protein kinase A ----- Glycogen metabolism pathway in mind, will glucose level decrease or increase in blood in the following scenarios? Provide reasoning for your answer.

a. G? subunit loses its activity to hydrolyze GTP.

b. G?? subunit can not be separated from f G? subunit

c. Phosphodiestersae is overactive

d. PKA’s affinity is lowered for cAMP.

e. GRK is inhibited

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Deanna Hettinger
Deanna HettingerLv2
28 Sep 2019

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