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The kcat for the GTP hydrolysis by the G? subunit of a heterotrimeric G protein is 0.026 /min How long will a single molecule of G? be active?

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Patrina Schowalter
Patrina SchowalterLv2
28 Sep 2019

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Related questions

10 A) Which of the following statements about phospholipase C signaling is true?

It cleaves an inositol derivative into membrane-associated IP3 and diffusible DAG.

Upon GPCR activation, GDP is replaced by GTP on the G-alpha subunit, which directly activates phospholipase C.

DAG and IP3 are intimately involved in intracellular Na+ signaling.

The substrate of phospholipase C is inositol.

10 B) Of the components of a heterotrimeric G protein, which subunit is able to activate downstream responses?

only the ? subunit

only the ? subunit

only the ?/? subunits

both the ? subunit and the ?/? subunits

What is a heterotrimeric G?protein? What is the role of each subunit of the trimer. Explain how this protein is switched on by the ??adrenergic receptor. Why is a g-protein sometimes called a time switch?

Which of these is not true about the beta-gamma subunit of the heterotrimeric G protein often coupled to 7TM-receptors? Provide explanations for the answers you choose and do not choose.

A. it does not change conformations

B. when in heterotrimeric form, it increases affinity of alpha subunit for GDP

C. it consists of the GTPase domain and the alpha helical domain

D. the subunits are bound together by covalently attached lipid molecules

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