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How many STR(short tandem repeats) loci are required to assist in solving a crime in a series of citites of increasing population size such as Canberra, Papua New Guinea and Indonesia using an online STR database

Check list of the minimum statistical analysis required

• Standard Statistics: Number of alleles Na, observed heterozygosity HO, expected heterozygosity

HE for all loci. Also report the mean of these values over the loci.

• DNA Profile probabilities DPP, across all 15 loci for two different individuals.

• Cumulative PI for increasing combinations of the 15 loci.

• Compute the odds for all probabilities that you calculate (e.g. DPP and PI).

Assess whether the STR database populations approximate HWE (F=0).

• Compute the degree of differentiation (FST) among the populations in the database.

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Keith Leannon
Keith LeannonLv2
28 Sep 2019

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