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Describe what happens in a bone marrow transplant with respectto blood cells,stem cells and development/differentiation. Whywould this procedure be used?

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Bunny Greenfelder
Bunny GreenfelderLv2
28 Sep 2019

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Related questions

Module 6 problem

For this module you must research a stem cell treatment. Explain the problem that the stem cells will treat, what type of stem cells are being used and what model it is used in, for example mice or humans. Bone marrow transplant will not be an acceptable answer.

1.A mouse is heterozygous at twoloci. Its genotype is AaBb. What gametes (and inwhat proportion)would be produced if the mouse undergoes meiosis and A and Bare ondifferent chromosomes. What gametes would be produced and inwhatproportion if A and B are very close together on the samechromosome. If the tworesults are different why are theydifferent?

2.Describe what happens in a bonemarrow transplant with respect to blood cells,stem cells anddevelopment/differentiation. Why would this procedure beused?

QUESTION 1

How is a bone marrow transplant able to treat someone with leukemia?

The donor blood contains antibodies that destroy cancer cells

Donor blood contains stem cells that regenerate cells in the immune system

Bone marrow contains induced pluripotent stem cells that turn into red blood cells

Bone marrow contains tumor supressor genes that slow down leukemia growth

Bone marrow contains pluripotent human embryonic stem cells

1.2 points

QUESTION 2

What would happen if siRNAs designed to target mRNA from an oncogene were introduced into cancer cells?

Increased genomic instability would result from adding foreign nucleic acids

New mutations would arise in the oncogene

The oncogene would be converted back into a proto-oncogene

The siRNAs would compete with the oncogene's active site

Production of the oncogene protein would decrease

1.2 points

QUESTION 3

What is the purpose of chromatin-remodeling enzymes in human cells?

The enzymes control the rate of translation of an mRNA transcript

The enzymes add phosphate or methyl groups to histone tails

The enzymes slide nucleosomes farther apart or closer to each other

The enzymes send damaged proteins to the proteasome for degradation

The enzymes cause DNA looping to occur

1.2 points

QUESTION 4

If you wanted to resurrect the mammoth, how would you do it?

Use somatic cell nuclear transfer to insert the mammoth genome into the egg of an elephant

Use transcription factors to re-program adult cells from elephants into mammoth cells

Change the gene expression patterns of elephants to increase production of mammoth genes

Use siRNAs to decrease expression of elephant-specific genes in an elephant embryo

1.2 points

QUESTION 5

How is eukaryotic transcription initiated?

RNA polymerase is recruited to the start codon by transcription factors

RNA polymerase begins transcription at the enhancer sequence

RNA polymerase is activated by binding to GTP

An initiator tRNA binds to the ribosome

A complex of proteins forms at the promoter of a gene

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