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What two stages of the cell cycle is the protein Cdt1 now known to participate in and what role does it play in each?

What is the end result if Cdt1 function is blocked?

Explain how Cdt1, the protein Hec1, and kinetochores all interact.

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Lelia Lubowitz
Lelia LubowitzLv2
28 Sep 2019

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Related questions

In your effort to understand what may be wrong with individuals carrying a mutant pretendin gene, you decide to try a little bioinformatics.

With the help of a computer program that allows you to compare a protein sequence to all other known protein sequences to find regions of high similarity between them, you find that pretendin is very similar to another protein called madeupin, which binds to kinetochores in mitotic chromosomes. Furthermore, you discover that the now famous L>E pretendin mutation that you've been investigating so far happens within an amino acid sequence of pretendin that is almost identical to a region of madeupin known to be critical for its ability to bind kinetochores and facilitate the latching of spindle microtubules to chromosomes.

In 150 words or fewer, formulate a hypothesis addressing the following points:

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-What could happen to the chromosomes of cells with mutant pretendin during mitosis?

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