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You have a couple who are thinking of having children. The wife has A blood type and is a carrier for sickle cell anemia; her father had O blood type. The husband has B blood type and is a carrier for b-thallassemia; his mother had A blood type.

a) What is the probability that the couple has a son who is a carrier for sickle cell anemia and thallasemia?

b) What is the probability that the couple has a daughter who is NOT a carrier for either disease?

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Jean Keeling
Jean KeelingLv2
28 Sep 2019

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Related questions

Sickle cell anemia and albinism are both recessive traits inhumans. Imagine that a couple, already pregnant with twins, hasjust learned that they are both heterozygous for both of thesetraits. As the couple's genetic counselor, the couple asks you thefollowing questions about how their carrier status will affecttheir offspring.

1.

If the couple has fraternal twins, what is the probability thatboth children will be unaffected by both conditions?

2.

If the couple has fraternal twins, what is the probability thatboth of the couple's children will have both sickle cell anemia andalbinism?

3.What is the probability that one of the fraternal twins is acarrier of either, but not both, of the conditions?
(Hint: You will need to use both the product law and the sum law toanswer this question.)

4.

If the couple has fraternal twins, what is the probability ofhaving two phenotypically normal children, one being a carrier ofonly the sickle cell anemia recessive allele, and the other being acarrier of only the recessive allele for albinism?
(Hint: You will need to use both the product law and the sum law toanswer this question.)

A man and a woman each have one sickle-cell anemia allele. He iscolor blind, while she is a carrier for color-blindness. What isthe probability that a daughter will have both full-blownsickle-cell anemia and be colorblind? What is the probability thata son will have both sickle-cell anemia and be colorblind? Showyour work.

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