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26 Jun 2019
1. You want to determine the linear order and genetic distance between three genes on chromosome II in Drosophila. The recessive mutant alleles are g, m, and o. You cross heterozygous females to homozygous recessive males, score the phenotypes of progeny and obtain the following:
540 g m +
560 + + o
162 + m +
170 g + o
245 g + +
240 + m o
46 g m o
37 + + +
a) Determine the orientation of mutant vs. wild type alleles on the female parentâs chromosomes and then determine the gene order.
b) Calculate the distance between the three genes and draw the genetic map.
d) Calculate interference and provide a brief verbal interpretation of your result.
1. You want to determine the linear order and genetic distance between three genes on chromosome II in Drosophila. The recessive mutant alleles are g, m, and o. You cross heterozygous females to homozygous recessive males, score the phenotypes of progeny and obtain the following:
540 g m +
560 + + o
162 + m +
170 g + o
245 g + +
240 + m o
46 g m o
37 + + +
a) Determine the orientation of mutant vs. wild type alleles on the female parentâs chromosomes and then determine the gene order.
b) Calculate the distance between the three genes and draw the genetic map.
d) Calculate interference and provide a brief verbal interpretation of your result.
Irving HeathcoteLv2
28 Jun 2019
