BIO 360 Chapter Notes - Chapter 18: Phenylalanine Hydroxylase, Normal Route, Alpha-Ketoglutaric Acid

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asiaal

4 Oct 2022

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Chapter /81-11 1 problems : aspartate, glutamate a- ketoglutarate -1 aspartate oxaloacetate a- ketoglutarate -1 glutamate a- ketoglutarate. C - coo: alanine a- ketoglutarate -1 alanine pyruvate if. % - coo: phenylalanine a- ketoglutarate -1 phenylalanine phenylpyruvate. F-chi%- ooo: phenylalanine hydroxylase ; alow - phenylalanine diet, normal route of phenylalanine metabolism lyla hydroxylation -10 tyrosine) is blocked . This causes phenylalanine -10 accumulate : phenylalanine transformed tophenylpy. ru/atebytransaminat1on+phenyi1actate by reduction . Transom/nation reaction has an equilibrium constant 01-1. 0 + phenylpyruvate. Is formed insignificant amounts when phenylalanine accumulates: deficiency in production of tyrosine (precursor of melanin . "snh , i: citralline r - nh - c - " " coo : ornithine no labeled n in ornithine, arginine . R - mh - -15mhz: aspartate 15mhz. Transfer of nitrogen from nh> to carbon skeletons can be catalyzed by 1 glutamine synthetase and 2 glutamate dehydrogenase .

Related Questions

1. Which of the following can be produced through the pentose phosphate pathway?

A. ATP

B. pyruvate

C. NADPH

D. more than one of the above

2. Each of these amino acids is paired with its degradation intermediate except

A. serine --> pyruvate

B. lysine --> succinyl CoA

C. asparagine --> oxaloacetate

D. arginine --> alpha-ketoglutarate

3.Proline biosynthesis starts with the metabolic intermediate

A. oxaloacetate

B. a-ketoglutarate

C. pyruvate

D. 3-phosphoglycerate

4. Which of these cofactors is NOT a one carbon carrier?

A. THF

B. TPP

C. SAM

D. biotin

5. Glycine has pKa values of 2.1 and 9.0. For which pH would it BEST serve as a buffer?

A. 11

B. 8.3

C. 5.5

D. 3.1

E. 2.3

blushwoodchuck519

1. a) Briefly explain why many mammals are herbivores and eat grass and other plants for nutrition, whereas humans are unable to use cellulose as a food source.

b) Which of the following tripeptides (only one) would be most likely to be soluble in an organic (hydrophobic) solvent like benzene. Explain.

N - phenylalanine - alanine - aspartate - C

N - leucine - alanine - histidine - C

N - glutamine - asparagine - proline â C

N - methionine - phenylalanine - alanine - C

N - glutamine - asparagine - glycine â C

pearcockroach968

calculate the moles of ATP pergram for the complete aerobic metabolism of the following aminoacids.

NOTE: Be sure to oxidize theamino acid all the way to CO2.

Don't stop when you get to a Krebs cycle intermediate --go from oxaloacetate to PEP to pyruvate to acetyl-SCoA and thenoxidize the acetyl-SCoA to CO2 bygoing around the Krebscycle again.

Note: Whenever glutamate is produced in a transaminationreaction, recycle it to Î±-ketoglutarate (via the glutamatedehydrogenase reaction) and make ATP from the NADH.

a) alanine

b) arginine (assume that both dehydrogenases use NAD+, notNADP+, as an oxidizing agent)

c) tyrosine

d) isoleucine

pucefly616

BIO 360 Chapter Notes - Chapter 18: Phenylalanine Hydroxylase, Normal Route, Alpha-Ketoglutaric Acid

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