BIOL 118 Lecture Notes - Lecture 34: Antibody, Antigen, Epithelium

• School: University of San Diego
• Department: Biology Courses
• Course: BIOL 118
• Professor: Terry Bird

Document Summary

Attachment--bind to host cell via hemagglutinin & sialic acid (viral receptor) Specific viral receptor needed or else it can"t bind. Triggers a process called endocytosis(word may be seen on exam)--inward budding. Way for cell to take large sample from the environment. Envagenate (pull in) part of host cell membrane. Coated vesicle (inside membrane bound compartment still attached to the viral receptor) Tricks cell thinking its bringing in food particle & pumps acid for digestion. Evolved to do so (remember not living organism) When acid is pumped, hemagglutinin shapes changes (due to low ph) membrane around the virus fuses with the membrane surrounding the vesicle. Result: release of 8 rna subunits into the cytoplasm. Then migrate to the nucleus (for synthesis) Crucial bc this is where transcription occurs via rna polymerase. Assembly & transport then budding to leave the cell. For each new virus there has to be 8 subunits.