BIOL 118 Lecture Notes - Lecture 35: Antigenic Shift
Document Summary
Have general sense of steps involved of influenza. Immune response would make antibodies that can bind to either one of the proteins. Virus changes rapidly, and has multiple forms that is circulating around earth. What makes it difficult to make a vaccine. Available to every virus; gradual change over time (relatively slow) Changes are result of mutations that occur in the rna protein**** (consequence of mutations that happens to the rna molecules that codes for these proteins) The change is in the protein, it doesn"t lose the function. Could mutations occur that destroy the function of. Yes but will disappear bc can"t repro. Mutations that slightly change & don"t affect function will be selected for bc can repro better via avoiding immune system. Can stilll bind to viral receptor but antibody can"t. Direct consequence of how the viral genome is in 8 subunits**** Can occur in either genes that codes for the two protiens.