BIOS 230 Lecture Notes - Lecture 25: Bupivacaine, Heparin, Passover
Document Summary
Chapter 10: an outbreak fulminant hep b in a medical ward in israel (sanku et al. , 2017) Cluster of hepatitis b cases observed on medicine a ward exceeded expected. Cluster-associated case patients lacked plausible ways of acquiring infection outside of the hospital: find mechanism of transmission for the 1st cluster of 5 cases in june, determine if 6th case is connected to first 5. Analyze patients in medicine ward a in case-control study. Controls were patients who were found to be exposed to hepatitis b positive patients but did not die or test positive for hepatitis b. 10/11 patients who shared vial were seroconverted. Heparin lock was used in all cases compared to only 24% of controls. The time period in question was during passover, less staff on floor. Decide whether observation or additional studies are indicated. Perform additional analyses or plan and perform additional study. Perform new (investigation-derived) control measures and/or ensure compliance of existing control measures.
