BIO SCI 75 Lecture Notes - Lecture 5: Follicular Phase, Blood Vessel, Endometriosis

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Endometrial (menstrual) cycle: cyclical growth & degeneration of uterine endometrium (change thickness) over 1 month time under hormonal control (w/out pregnancy, phases: Proliferation (estrogen phase): healing & replacement of lost tissue. Secretion (progesterone phase): increase thickness, blood vessels & fluid secretion in preparation for embryo. Ischemia (degeneration, menstruation): blood vessel contract causing endometrium to degenerate; some blood loss. Cyclical maturation & release of eggs in the ovary: phases (names correspond to endometrial cycle): Follicular phase (corresponds in time with proliferation phase): follicle cells around the egg grown and develop fluid filled cavity (antrum) to form mature follicle, make estrogen. Ovulation under hormonal control mature follicle bursts releasing the egg with some attached follicle cells (corona radiata) Luteal phase (secretion): remaining follicle cells form the corpus luteum (endocrine gland, yellow) & make progesterone & estrogen. Estrogens (several of them, like estradiol) secreted by follicle cells. Small amount of androgen from adrenal cortex (gland on kidney)

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