BIO 115 Lecture Notes - Lecture 2: Bronchopulmonary Dysplasia, Dysplasia, Main Stem
Document Summary
Describe the stages of lung development and what changes occur during these times. Outpouching of the foregut into the mesoderm and begins to branch. Trachea, main stem, lobar, and segmental bronchi are formed lack smooth muscle, cartilage, and nerves. Mesenchyme tissue important to guide the branching. Vascular connections with the atria develop, but pulmonary and bronchial vessels are not well formed. Type 1 alveolar cells: thin, elongated cells that increase the sa of the lung to facilitate gas exchange. Type 2 alveolar cells: produce surfactant to maintain alveolar inflation. More development of alveoli, and this development may persist until. Define bronchopulmonary dysplasia and identify the factors that increase/decrease the adolescent age risk of developing bronchopulmonary dysplasia. Terminal bronchioles and primitive acinar structures are formed. Pulmonary vasculature develops parallel to bronchi and bronchioles. More branching to the point of primitive alveolar ducts and acinar tubules. Capillaries surround distal acinar tubules to form gas exchange region.
