BIO207 Lecture Notes - Lecture 3: Toxic Shock Syndrome Toxin, Disseminated Intravascular Coagulation, T Helper Cell
Document Summary
Gram-positive pathogens of medical importance: gram positive produces much milder inflammatory processes. Gram negative have an lps which causes hyper stimulation of immune system, Staphylococcus aureus: staphylococcus aureus is gram positive, typically extracellular, commonly a commensal bacterium, but true pathogen. Can colonize and cause disease: causative agent of staph infections can be boils to ulcerative tissue and necrotizing fasciitis. Can also cause blood infection leading to sepsis and toxigenic shock: staphylococcus aureus is one of leading causes of septic shock/death in the world, methicillin resistant staphylococcus aureus and vancomycin resistant. Streptococcus pyogenes: streptococcus pyogenes is an extracellular, aero tolerant gram-positive streptococcus, commonly found in the space around the tonsils. Transmission is usually through human-human contact, but cattle also can be colonized (utters: streptococci are nomenclature through the lancefield i. d. system which account for serology and hemolysis potential. Bacillus anthracis: bacillus anthracis is a gram-positive, spore forming, streptobacilli. It is extracellular: common farm-based bacteria (is an obligate pathogen).