Microbiology and Immunology 3820A Lecture Notes - Lecture 9: Fibronectin, Toxic Shock Syndrome Toxin, Postpartum Infections
9 Dec 2016
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Coagulase positive enzyme test that is its positive, your always talking about staph aureus. If its negative, you"re talking about one of the non-staph aureus. Inhabits anterior nares, skin and throat, between fingers. The only reason you do posterior nasal is to confirm whooping cough. Technologists look at colonies, do a gram stain and so special tests. Our normal flora organisms don"t cause us any trouble (unless they get into the wrong place). Cell wall virulence factors: protein a: binds to fc portion of igg and inhibits antibody directed phagocytosis, fibronectin-binding protein (fnbp): (cold soluble globulin). Most normal things precipitate when you cool it down and returns to normal when you warm it up. This strange thing precips at room temp and solubilizes at room temp. Fibronectin coats all respiratory mucosa and occupies spces that gram rods like to bind to. Staphaureis can bind to anything it stays there no matter what.
