01:119:116 Lecture Notes - Lecture 25: Fluid Balance, Hemolymph, Coronary Circulation
18 Jun 2020
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Chapter 42. 4 and 43. 1: components and functions of mammalian blood. Functions of the blood: transport, maintain fluid balance, defense against pathogens. Composition of the blood: 55% plasma liquid matrix, 45% cellular elements, red blood cells (rbcs, white blood cells (wbcs, platelets, plasma composition. Pale yellowish fluid that consists of: 92% water. Inorganic salts= ions= blood electrolytes: plasma proteins. Hormones: cellular elements in the blood, origin of cellular elements: Produced in red bone marrow of certain bones (ex: ribs, vertebrae, sternum, pelvis) Most numerous= ~25 trillion erythrocytes in average adult. 5 - 6 million/cubic mm (microliter) of blood. Flexible biconcave discs (elastic framework)--> bend pass through tiny capillaries in mammals: no nuclei and no mitochondria. Contain hemoglobin= iron-containing protein function is to transport )2 and give blood red color. Color of erythrocyte production: controlled by hormone erythropoietin (epo)= produced y kidneys, negative feedback mechanism= sensitive to amount of o2 reaching tissues.
