01:119:115 Lecture 8: Lecture 8

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Cellular respiration: a catabolic pathway (release stored e in food in presence of oxygen) using. Digestive system hydrolysis: carbohydrates simple sugars, proteins amino acids, fats glycerol + fatty acids. Redox reactions: transfer of electrons between reactants: oxidation: loss of electrons (h) oxidized reducing agent, reduction: gain of electrons (h) reduced oxidizing agent. Nadh: stored e used to make atp: nad+ is electron shuttle/h acceptor. Dehydrogenases enzymes: remove 2 h (2 e, 2 p) from substrate oxidation, deliver 2 e and 1 p to nad+ nadh 1 h+ released in solution. Cellular respiration in prokaryotes (bacteria: no nucleus, no membrane-bound organelles, no mitochondria, aerobic respiration in cytosol, etc in plasma membrane, all same phases as eukaryotes, but more atp produced (all nadh in cytosol) Stages of cellular respiration in eukaryotes: glycolysis (glucose-splitting) in the cytosol, glucose 2 pyruvates. Glucose enters cell via facilitated diffusion (in mammals) by glut1 (protein); no oxygen required. Needs atp (endergonic) delta g is negative.

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