01:119:115 Lecture Notes - Lecture 8: Pyruvate Dehydrogenase, Oxidative Phosphorylation, Oxidizing Agent

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These enter the bloodstream and are used by cells for respiration. Energy from electrons is used to make atp. Carbohydrates, proteins, and fats are broken down into simple sugars, amino acids, glycerol, and fatty acids: Using electron transfer -> movement of electrons -> energy is released. Oxidation reaction: loss of electrons (one or more) -> is oxidized. Molecule can be oxidized by losing an h. Molecule can be reduced by taking an h. H takes electron with it and transfers energy to the h acceptor. Dehydrogenase enzymes: remove pair of h (2 electrons and 2 protons) from substrate -> oxidation, deliver 2 electrons and 1 proton (h+) to nad+ -> nadh -> 1 h+ released in solution. Nad+ (nicotanimide adenine dinucleotide) = known h acceptor. Chemical energy in bonds of nutrients -> chemical energy in atp -> energy used for cell. Anaerobic: does not require o2 (produces less atp)

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