01:119:115 Lecture Notes - Lecture 8: Nicotinamide Adenine Dinucleotide, Pyruvate Dehydrogenase, Oxidative Phosphorylation
2 May 2016
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Document Summary
Carbs, proteins, fats simple sugars, amino acids, glycerol+ fatty acids bloodstream transfer bloodstream cells cellular respiration. Catabolic pathways release stored energy in food. Using electron transfer electrons move energy is released. Oxidation: loss of electron (one or more) is oxidized. Molecule can be oxidized be losing an h. H takes electron with it and transfers energy to the h acceptor. Nad+ (nicotinamide adenine dinucleotide) = known h acceptors. Nadh has stored energy used to make atp. Dehydrogenases enzymes: remove pair of h (2 e- and 2 protons) from substrate oxidation, deliver 2 electrons and 1 proton (h+) to nad+ nadh. Cellular respiration: converts: chemical energy in bonds of nutrients chemical energy in atp energy used for cell work, can be: aerobic: uses o2 anaerobic: does not require o2, occurs in all cells prokaryotes eukaryotes. C6h12o6 + 6o2 6co2 + 6 h2o + e (in atp) Redox reactions transfer of electrons from nutrients. Catabolic reaction: exergonic delta g is -686 kcal/mol.
