PSYC-251 Lecture Notes - Lecture 8: Anorexia Nervosa, Antipsychotic, Autopsy

• School: Georgetown University
• Department: Psychology
• Course: PSYC-251
• Professor: Jesse Brand

Document Summary

Hu(cid:374)ti(cid:374)gto(cid:374)"s disease inherited disorder resulting in death of brain cells. Often begins with mental/mood disorders and progresses to physical impairments such as jerky body movements typically inherited from parents in autosomal dominant pattern. 10% of cases are inherited from parents. More repeats = more severe / earlier onset. Produces an abnormal protein in the brain. Most damage is to the basal ganglia on mri, which causes chorea, rigidity, abnormal posture, difficulty with speech. Cognitive impairments: short-term memory, cognitive flexibility, long-term memory, abstract thinking, rule acquisition, planning. Death usually comes 20 years after the onset of noticeable symptoms due to pneumonia ( 1/3 of hu(cid:374)ti(cid:374)gto(cid:374)"s pts (cid:449)ill die fro(cid:373) p(cid:374)eu(cid:373)o(cid:374)ia (cid:895), heart disease, or sui(cid:272)ide. Suicide risk comes from the mood effect. Physical therapy, occupational therapy, speech therapy, tetrabenazine can treat chorea, Ssris can treat psychiatric symptoms, other antipsychotic drugs. Primary progressive aphasia neurological syndrome in which language capabilities become slowly and progressively impaired.