BIOL2000 Lecture Notes - Lecture 15: Maturation Promoting Factor, Open Reading Frame, Gene Expression
16 Jan 2017
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Document Summary
Genes: dna sequences, on chromosomes, units of inheritance. Each diploid: 2 copies (alleles) of each gene in each cell. One allele from dad one from mom. Mutant alleles are useful in defining bio role of gene. Gene expression (transcription and translation) allows rna and protein to be produced. Gene: not just dna that encodes, also includes regulatory info that controls gene expression. Gene expression: production of functional product (rna or protein) from a gene. Dna , transcription, rna (synthesis, processing, degradation), translation, protein (synthesis, post trans mod, localization, degradation) Transcription: synthesis of singel stranded rna comp to dna template strand. Phospho bond by rna polymerase after base pairing. Adding based on presence of 3 prime hydroxyl and 5 prime tri phosphate. Open reading frame: stretch of sequence that starts w start codon (atg) and ends w stop codon (tag, taa, tga) Diff btw dna and rna: need for primer. Dna uses primase to lay down rna primer then replicated dna.
