Biology 1001A Lecture Notes - Lecture 7: Thymine
20 Oct 2015
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Document Summary
A double stranded change in dna is defined as a mutation. Mutation that occurs in the somatic body are not exemplary evolution; does not get passed on to offspring only heritable variation is important to offspring: only mutations that occur that change your gametes will affect offspring. Movement sometimes occurs from copy/paste; sometimes occurs by reverse transcription (retrotransposons) retroviruses can move within genomes. Comparison of snps in 10 personal genomes; more african variation. Modern people of african descent are much more variable than people of asian descent/caucasian this is because african populations are believed to be the oldest had the longest time to accumulate variability. Snps arise from replication errors spontaneous tautomeric shifts change base pairing partners all nitrogenous bases in human. Mutations occur because of the inherent instabilities in the bases. Dna can be fooled and add 5-bromouracil instead of uracil.
