Biology 1001A Lecture Notes - Lecture 7: Guanine, Cytosine, Adenine
6 Dec 2017
School
Department
Course
Professor
Document Summary
A mutation does not have to be in a coding region for it to be called a mutation. A double stranded change is the only needed for it to be a mutation. Clear majority of variants are snps (single nucleotide polymorphism) About 2500 structural variations including mobile elements, copy number variation (cnv) inversions etc. Some of us have chromosomes that are structured differently than others. About 30 variants are associated with disease. Bacterial elements code for their own mobility (transposase): Is elements: are essentially guys who pick up couches and move them into other rooms (or pick up coding sequences and move them to where they need to be) Transposase: a recombining enzyme that allows the dna to send copies of itself around the chromosome. Transposons: move coding sequences, almost like copy and pasting them. When dna polymerase gets involved, it copies and pastes them through the method of recombination.
