Biochemistry 2280A Lecture Notes - Lecture 16: Mitochondrion, Cytosol, Pyruvate Dehydrogenase
18 Dec 2015
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Biochem lecture 16 acetyl coa 1: the citric acid cycle. Pyruvate is made in glycolysis which is made in cytolsol. But acetyl-coa is made in mitochondria ( as well as citric acid cycle) Identify the different metabolic fates of pyruvate, and how these pathways are related. State the net reactions for the conversion of pyruvate to acetyle- coa and co2, and for the citric acid cycle (including stoichiometries) State the metabolic circumstances under which oxidation of pyruvate and the citric acid cycle are favoured, without memorizing individual regulators. Many small pores that allow small molecules (<5000 da) to cross. Proteins structures that make pores fairly large that allow small. Not much of a barrier to small molecules. Prevents ions and polar molecules from crossing, unless a special. Pink one, also a lipid bilayer, much more restrictive of what can cross, The space enclosed by the inner mitochondrial membrane; inside of. Pyruvate gets transported in here the mitochondria.
