BIO130H1 Lecture Notes - Lecture 11: Rna Polymerase Ii, Garland Science, Consensus Sequence

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23 Feb 2016
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BIO130H1 Full Course Notes
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BIO130H1 Full Course Notes
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Bio130 lecture 11 processing and termination. Before reading week, we were discussing: rna processing. Phosphorylation of the c-terminal tail of rna polymerase ii results in the binding of rna processing proteins. Rnap is transcribing a gene, with some false starts, it really gets going when the phosphorylation begins: factors are attracted, like the 5" capping enzyme. Not everything that is needed will be present on the mrna, especially with. People didn"t know at first that introns existed. Hexon gene with upstream sequences that happen to come from adenovirus. What people discovered were these intervening sequences that were eventually. The diagram is one of the first examples discovered taken out in the final mrna: these were named introns (iii in the diagram, xyz are exons. Rna processing increases the number of gene products. Diagram shows double-stranded dna for alpha- tropomyosin gene: master gene , dark orange is exon, light orange is intron.