BIO130H1 Lecture Notes - Lecture 2: Hemoglobin, Hydrophile, Hydrophobe

• School: UTSG
• Department: Biology
• Course: BIO130H1
• Professor: Newmann

Document Summary

Interactions between individual molecules usually mediated by non covalent attractions: electrostatic attractions, hydrogen bonds (strongest when straight, van der waals attractions (flickering dipoles, dynamic/moving through the molecule, not weakened by water, hydrophobic force (forces hydrophobes together) ==> individually very weak forces, but can sum to generate strong binding between molecules. Nucleic acid chains: dna synthesised from deoxyribonucleoside triphosphates > dntps (n can be any base: actg, rna is synthesised from ribonucleoside triphosphates > ntps (n: acug, nucleotides are linked by phosphodiester bonds (a covalent bond, so strong!) Phosphate linked to 5" c of next nucleotide (phosphodiester bond) Base pairing: (complementary: holds double helix together (h bond holding the bases together are planar, straight, a -t > 2h bonds, c - g > 3h bonds. Dna structure: the most thermodynamically stable structure (all forces aforementioned are involved in creating this stability) The strands in a double helix are parallel > one strand is 5" > 3" while its partner is 3".