BIO130H1 Lecture Notes - Lecture 2: Messenger Rna, Transfer Rna, Endosymbiont

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10 Jan 2019
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BIO130H1 Full Course Notes
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BIO130H1 Full Course Notes
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Eukaryotic cells appear a billion years after prokaryotic cells. 3 lines of evidence to support endosymbiont theory. Mitochondria and chloroplasts have remnants of their own genome prokaryotic appearance. Mitochondria and chloroplasts have also kept their own protein dna synthesis components, some transport machinery. Mitochondria and chloroplasts have a double membrane: composition of inner and outer membrane is really different, possible that it originated from the ancestral aerobic prokaryote itself and the other from host cell when this organism was eaten. Took the ribosomal rna gene sequences of cells and lines them up to see their evolutionary history. 19th and early 20th century approach late 20th and 21st century approach. Using model organisms (representations: general attributes rapid development with short lifecycles, small adult, readily available, tractability (ease of manipulation or modification), understandable genetics (haploids and diploids are easier to understand)) Sequence its genome and apply these findings to other organisms.