BIO120H1 Lecture Notes - Lecture 5: Neo-Darwinism, Genetic Drift, Heterozygote Advantage
24 Sep 2018
School
Department
Course
Professor
BIO120H1 verified notes
5/25View all
Document Summary
Bio120 lecture 5: genetic variation: models and. September 24, 2018 (relevant reading why evolution is true, coyne: chapter 5) These people differ on average by millions of genetic changes in their genome sequence. 1930-1950 theoretical population genetics was initiated by fisher, haldane % wright and provided foundations for neo-darwinism and the new synthesis . They showed that continuous variation and darwinian natural selections were entirely consistent with mendel"s laws. They also demonstrated the evolutionary significance of genetic variation leading to several key questions and development of the field of ecological and evolutionary genetics. Mutations: ultimate source of genetic variation, caused by errors during replication (not directed, mutations can persist in populations and become more popular or less common. Introduces new combinations of mutations into a population. Random genetic drift: random sampling effects every generation becomes more important as populations become smaller. Different processes can increase or decrease genetic diversity within populations.
