HSS 1100 Lecture Notes - Lecture 12: Infectious Mononucleosis, Attenuated Vaccine, Neonatal Infection

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: William Yan

Document Summary

Hss1100 lecture #12 viruses part 2. Mumps: childhood disease; bilateral inflammation of parotid glands; many in apparent infections, complications: meningitis, orchitis (can lead to sterility), ovaritis, epidemiology: spread by salivary and respiratory secretions; incubation 18- 3=21 days: prevention: mmr vaccine (live, attenuated) Diagnosis: blood picture (in atypical lymphocytes) monospot test (detects rbc agglutination) presence of ebv antigens. Isolation of virus from urine, blood, organ biopsies (slow process, but accurate: cmv antigen detection, dna hybridization and pcr in leucocytes much faster, serology screening for donors and recipients before transplant. Prevention (immunocompromised): match cmv immune status between donor and recipient in transplant, preventative administration of antivirals, universal precautions to prevent transmission, no vaccine. Hepatitis = inflammation of the liver: malaise, fatigue, nausea, loss of appetite and jaundice. Hep a, b most common and well characterized: hep c,e,g less common. *other viruses and bacteria can cause hepatitis as a complication of infection*