HSS 1100 Lecture Notes - Lecture 8: Mycobacterium Tuberculosis, Mantoux Test, Mycobacterium Fortuitum

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: William Yan

Document Summary

Chronic slow-process pulmonary infection; transmission by aerosol droplets. 4-6 weeks to see colonies on a plate: lowenstein-jensen medium, use microscopy of sputum smears as first line of diagnosis. Leading cause of death world-wide form a single infection (bacteriology, kenneth todar: affects 1. 7 billion/year, declining in us. Post-primary tuberculosis: late reactivation of lesions in lung, kidneys, bones etc, 5% of cases; higher in patients with aids, chronic infection. Immunity in tuberculosis cell mediated immunity is most important (t-cells) Mantoux test tuberculin solution is injected intrademally, wait 48-72 hours, check for induration record diameter of induration: >10mm positive, 5-9mm doubtful, maybe cross reaction with other mycobacteria, <4mm negative. **a positive test does not necessarily mean there is currently an active infection*: doesn"t matter if the area turns red, only matters if it raised, the shit that they put in your arm is called tuberculin.