HSS 1100 Study Guide - Final Guide: Microbiological Culture, Cefuroxime, Venereal Disease Research Laboratory Test

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: William Yan

Document Summary

Mycobacterium tuberculosis: acid-fast bacillus causing chronic, slowly progressing pulmonary infection, obligate aerobe. Primary tuberculosis: aerosol inhalation of tubercle bacilli start multiplying in lung alveoli -> move to the hilar lympth nodes, macrophage ingestion of bacilli and formation of primary complex. Foci of infection in lungs (may be spread to kidneys, bones, mininges) 6 weeks after the onset, cmi is fully active, infection is stopped (majority of cases) The latent infection and the active cmi is reflected in a positive tuberculin test. Tuberculin = protein obtained by concentrating and purifying the liquid culture medium in which. Latte reactivation of silent lesions in hosts who have developed a certain degree of immunity (tuberculin positive: reinfection (infection with diff strain) occurs rarely. Non-tuberculous (atypical) mycobacteria: occasionally isolated from patients with chronic pulmonary disease indistinguishable from tuberculosis, m. marinum skin infections, m. fortuitum soft tissue abscesses. Mycobacterium leprae: causative agent of leprosy (hansen"s disease)