BIO 3302 Lecture Notes - Lecture 11: Hemoglobin, Vasoconstriction, Nfkb1

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Lecture 11 - birds vs mammals, also diving. Cross current flow is more efficient than counter current flow. Air sacs associated with bird lung account for 80% of o2 uptake. Glomus cells in fish detect water and/or blood o2 and co2 levels. Neuroepithelial cell in fish, glomus is in mammal. Increases in cerebrospinal pco2, cause hyperventilation in a goldfish. False - fish lack brain co2 sensors fish respond more strongly to oxygen than co2. Oxygen is main driving force for fish, chemoreceptors in gills, can detect co2, but key driver is oxygen. Low solubility --> focus on oxygen as ventilation thing. Central chemoreceptors -- brain chemoreceptors that monitor co2 and adjust accordingly. There are peripheral ones that will also detect oxygen and adjust but it"s mainly the co2. Air breathers breath less air --> get rid of waste less --> co2 builds and is noticed. Much lower convection requirement for uptake in air.

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