BIO 1140 Lecture Notes - Lecture 8: Exocytosis, Guanine, Aldosterone

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Important for development, immunity, physiology, cell growth/survival, hormonal regulation/homeostasis. Reception transduction responds: chemical messagers 6 class. Their structure will be determine; chemical properties, communication path, and modes. Classes: steroids, lipids, peptides/proteins, purines, amines, gases, steroids. Lipophilic (cant be stored in vesticles) will diffused or be bound to transport protein. All hydrophilic(reserve pool in vesicles) besides thyroids which are hydrophobic. Direct and indirect paths: cell communication paths. Farther pathways the most possibility it can be lost autocrine whatever has been release can comes back and acts on the cell paracrine cell will release messenger and act on neighbouring cells. endocrine blood streams. Nature of chemical path, the property will determine the pathway it will take. Interaction with the receptors is the first level of discrimation (set the path to the cells response) Receptors are proteinsl they can be on cell surface or inside. Ligand(messenger) binding will induce a change in conformation the receptor protein.