BIO 1140 Lecture Notes - Lecture 10: Paracrine Signalling, Lipophilicity, Signal Transduction
18 Feb 2017
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Document Summary
Imply change of events in cell to respond to it. Cell communication: first needs a message, nature of the message, who sends the message and how, where is the message sent, how is the message received, need receptors to receive the message. Interpret the message: decide how to react to the message and to do that we need to read it, and the message is amplified, act upon the message. Neutral activity involves transmission of information via electrochemical events in contrast endocrine activity involves transmission of information via hormone transport to target tissues. Indirect cell communication know what these do. The interaction with receptors is the first level of discrimination (set the path to the cell response) Ligand (messenger) binding will induce a change in conformation of the receptors protein. This acts as the trigger for the next phase: signal transduction.
