BIO 1140 Lecture Notes - Lecture 14: Start Codon, Transfer Rna, Response Element
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Know, describe and/or compare the diferent elements of control for gene expression in prokaryotes vs eukaryotes (acivators, enhancers, repressors, alternaive splicing, operons, interference) Transposons and retrotransposons: be familiar with what they are, be able to briely explain how they occur. In prokaryotes, dna is directly transcribed to mrna. In eukaryotes, dna is transcribed to a pre-messenger rna, that will be matured into mrna, and then be transported out of the nucleus. Need a hollow enzyme (rna polymerase), an enzyme built with muliple subunits. One is the sigma factor, to iniiate transcripion you need all the subunits to bind to the promoter region to iniiate transcripion, once transcripion starts and polymerase has begun transcribing the sigma factor can detach. The sigma factor means it"s free to meet up with an other incomplete complex (form another or the same gene). When you reach the end, the coding region detaches.