BIO 1140 Lecture Notes - Lecture 14: Enzyme, Rna, Mature Messenger Rna
Document Summary
Bio - lec 14 - transcription pt 1. Transcription of dna to rna : 5" to 3" Rna is oriented 5" to 3", therefore it is complementary to 3" to 5" dna strand rna polymerase ii. Reads the 3" to 5" dna strand, making the 5" to 3" complementary rna strand. Grabs all new nucleotides (not just replacing t for u) , Dna is transcribed to pre-messenger rna (extra step to mature into mrna), then it is transported out of the nucleus. Rna polymerase binds to promoter region to initiate transcription sigma units detaches, transcription continues. Sigma factor travels to attach to another incomplete rna polymerase, and initiate transcription elsewhere. At the end of coding region , rna polymerase detaches. To initiate transcription : needs proteins to bind, to recruit polymerase (tic - transcription initiation complex) Promoter region : protein binds to tata box, recruits other proteins (tata binding proteins)