BIO 1140 Lecture Notes - Lecture 16: Start Codon, Transfer Rna, Covalent Bond

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Bio - lec 16 - translation & protein sorting. Start : aug - methinine (translation begins with methinine - aug) All other combinations correspond to amino acids (20) More than one codon for each amino acid (flexibility) More than one codon for the same amino acid. Wobble effect/oscillation : allows to have fewer trna to have same effect (efficiency) Can get away with making fewer trna (codons) Tools that cell uses to match the codons on mrna, and ensure to bring correct amino acid & at the right time. Bottom portion (anticodon) , 3 nucleotides that are complenentary to codon. When there is a match, the amino acid is transferred from trna to growing polypeptide chain. Bind amino acid at 3" end of trna. 20 different ones (more efficient to have the same number as amino acids) Aminoacyl-transferase have specific binding sites/pockets that allow them to bind with only one specific amino acid.

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