ANP 1107 Lecture Notes - Lecture 17: Afferent Arterioles, Metabolic Alkalosis, Glutamine

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1107
• Professor: Jackie Carnegie

Document Summary

Intracellular fluid compartment (icf): within cells 60% total body fluid. Extracellular fluid compartment (ecf): 40% body fluid, 2 areas blood plasma ~20% of ecf; interstitial space - ~80% ecf, includes fluid i(cid:374)side (cid:272)ells, fluid that a(cid:396)e(cid:374)"t i(cid:374) (cid:272)ells (cid:271)ut i(cid:374) a(cid:374) a(cid:396)ea of the (cid:271)od(cid:455) (cid:894)i. e s(cid:455)(cid:374)o(cid:448)ial fluid (cid:271)t(cid:449)(cid:374) joints, eye liquid, fluid during exchange. Electrolytes have greater osmotic power than non-electrolytes b/c. Ecf major cation is na+, chief anion is cl-; icf major cation is k+, and chief anion is hpo4: na+ and k+ are opposite, when comparing ecf and icf, atp-dependent na/k pumps keep intracellular. Na+ concentration low and maintain high intracellular k+ concentration: renal mechs can reinforce these ion distributions by secreting k+ and na+ is reabsorbed from filtrate. Water balance water intake must = water output. Intake = liquids, foods, cellular metabolism; output = ~60% via kidneys, lungs, skin, sweat, feces.