ANP 1107 Lecture Notes - Lecture 3: Internal Sphincter Muscle Of Urethra, Urethral Sphincters, Oncotic Pressure

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Refers to the volumes of plasma from which the kidneys clear (completely remove) a particular substance in a given time. (per minute) U= concentration of the substance in the urine. Inulin is the substance used to determine the gfr. U= 125 mg/ml p= 1 mg/ml v=1 ml/min. Rc: c= (125 x 1)/ 1 = 125 ml/min. **this means: that in 1 minute the kidneys have cleared all the insulin present in 125 ml of plasma. If c is less than insulin - means the substance is reabsorbed. If c= 0 reabsorption is complete or the substance is not filtered. If c= inulin, there is no net reabsorption or secretion. Is c is greater than inulin; the tubule cells are secreting the substance into the filtrate. Creatine, which has a c value of 140 ml/min, is freely filtered but also secreted in small amounts. Freshly voided urine is clear and pale to deep yellow.

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