PHGY 214 Lecture Notes - Lecture 4: Glut2, Ketogenesis, Glycogenolysis
11 May 2016
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Document Summary
Endocrine pancreas, describe fuel metabolism in the liver, adipocyte, muscle, and brain during fasted and fed conditions. In fuel metabolism nutrient molecule are first broken down into smaller absorbable molecules. Two types of metabolism take place in the body: building up (anabolism) and breaking down (catabolism) Anabolism usually requires atp and result in the storage, structural, and functional macromolecules in cells. Amino acids are used to build body proteins (mainly in muscle) Glucose is stored in the liver and muscle as glycogen. Fatty acids are stored as triglycerides in adipose tissue. Catabolism hydrolyzes larger cellular molecules into smaller subunits and oxidizes smaller units to yield atp. The by-products are used as metabolic fuel in cells. Amino acids (and proteins) are eliminated from the body as urea. Glucose (and glycogen) are oxidized to create atp. Fatty acids (and triglycerides) also create atp.
